Name: Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce
Prep time: 10 min
Cook time: 20 min
Total time: 30 min
Cuisine: American
Ingredients: 2 chicken breasts; 2 tbsp Cajun seasoning; 2 tbsp olive oil; 8 oz spaghetti; 2 tbsp butter; 3 garlic cloves, minced; 2 tbsp all-purpose flour; 1 1/2 cups chicken broth; 1 cup heavy cream; 1 1/2 cups shredded mozzarella cheese; 1/4 cup grated Parmesan cheese; Salt and black pepper to taste; Fresh parsley, chopped (optional, for garnish)

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This Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is the perfect blend of bold spices and indulgent comfort food. I cook tender chicken breasts with Cajun seasoning, then coat everything in a luscious garlic mozzarella cream sauce that clings beautifully to strands of spaghetti. It's rich, spicy, cheesy, and incredibly satisfying.

Why You’ll Love This Recipe

I love how this dish brings together the smoky heat of Cajun spices with the soothing creaminess of garlic and mozzarella. It's a quick and hearty meal that feels restaurant-worthy but is incredibly easy to make at home. The balance of heat and cream makes every bite comforting with just the right kick. Plus, it’s a one-pan wonder that’s perfect for busy weeknights or a cozy weekend dinner.

Ingredients

(Here's a tip: Check out the full list of ingredients and measurements in the recipe card below.)

Chicken breasts
Cajun seasoning
Olive oil
Spaghetti
Butter
Garlic cloves, minced
All-purpose flour
Chicken broth
Heavy cream
Mozzarella cheese, shredded
Parmesan cheese
Salt and black pepper
Fresh parsley (optional, for garnish)

Directions

I start by seasoning the chicken breasts generously with Cajun seasoning.
In a large skillet, I heat olive oil and sear the chicken until it’s cooked through and golden on the outside. Then I remove it from the pan and set it aside.
While the chicken rests, I cook spaghetti according to the package instructions until al dente.
In the same skillet, I melt butter and sauté garlic until fragrant. I whisk in the flour to create a roux, cooking it briefly.
Gradually, I whisk in the chicken broth and heavy cream until the sauce is smooth and thickened.
I stir in mozzarella and Parmesan cheese until melted and creamy.
Then I slice the cooked chicken and return it to the skillet along with the drained spaghetti, tossing everything together to coat it in the sauce.
I finish with a sprinkle of parsley for a fresh touch.

Servings and timing

This recipe serves 4 people. It takes about 30 minutes to make from start to finish, making it an ideal quick dinner option.

Variations

I sometimes use shrimp instead of chicken for a seafood twist.
For a smokier flavor, I add a bit of smoked paprika to the Cajun spice mix.
If I want a spicier version, I toss in a pinch of red pepper flakes with the garlic.
I’ve also tried it with penne or fettuccine instead of spaghetti for a different texture.
To lighten it up a bit, I’ve substituted half-and-half for the heavy cream.

Storage/Reheating

I store leftovers in an airtight container in the refrigerator for up to 3 days. When reheating, I add a splash of milk or cream to loosen the sauce and warm it over low heat on the stovetop or in the microwave in 30-second intervals, stirring in between.

FAQs

How spicy is Cajun chicken spaghetti?

It has a mild to moderate heat level depending on the Cajun seasoning I use. I can always adjust the spice by reducing or increasing the seasoning.

Can I make this dish ahead of time?

Yes, I often cook the chicken and sauce ahead and store them separately. When I'm ready to eat, I just reheat everything and toss in freshly cooked pasta.

What type of mozzarella works best?

I prefer using low-moisture, part-skim shredded mozzarella because it melts smoothly and gives the sauce a great texture.

Can I freeze this dish?

I don’t recommend freezing it, as the cream sauce can separate and become grainy when thawed. It’s best enjoyed fresh or stored in the fridge for a few days.

What can I serve with Cajun chicken spaghetti?

I like serving it with a simple green salad or some roasted vegetables to balance out the richness.

Conclusion

Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is one of those dishes that brings warmth and bold flavor to the table with very little effort. I love how the Cajun spice plays off the creamy garlic cheese sauce and how it all comes together in one satisfying meal. Whether it’s for a casual family dinner or something a bit more indulgent, this recipe never disappoints.

Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

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Author: Sue
Prep Time: 10 minutes
Cook Time: 20 minutes
Total Time: 30 minutes
Yield: 4 servings
Category: Dinner
Method: Stovetop
Cuisine: American
Diet: Halal

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Description

A rich and spicy pasta dish featuring Cajun-seasoned chicken in a creamy garlic mozzarella sauce, perfect for a quick and indulgent dinner.

Instructions

Season chicken breasts generously with Cajun seasoning.
Heat olive oil in a large skillet over medium-high heat. Sear the chicken until golden and cooked through. Remove from skillet and set aside.
Cook spaghetti according to package instructions until al dente. Drain and set aside.
In the same skillet, melt butter and sauté garlic until fragrant.
Whisk in flour and cook for about 1 minute to form a roux.
Gradually whisk in chicken broth and heavy cream. Cook until the sauce is smooth and thickened.
Stir in mozzarella and Parmesan cheese until melted and creamy.
Slice cooked chicken and return to the skillet. Add the cooked spaghetti and toss to coat in the sauce.
Garnish with chopped parsley if desired and serve warm.