Print
clock clock iconcutlery cutlery iconflag flag iconfolder folder iconinstagram instagram iconpinterest pinterest iconfacebook facebook iconprint print iconsquares squares iconheart heart iconheart solid heart solid icon

Creamy Layered John Wayne Casserole

5 Stars 4 Stars 3 Stars 2 Stars 1 Star No reviews
  • Author: Sue
  • Prep Time: 20 minutes
  • Cook Time: 35 minutes
  • Total Time: 55 minutes
  • Yield: 12 servings
  • Category: Dinner, Casserole
  • Method: Baking

Description

This Creamy Layered John Wayne Casserole is the ultimate comfort food, loaded with seasoned ground beef, creamy cheese sauce, and fresh vegetables, all baked over a golden biscuit crust. Perfect for family dinners or casual gatherings, this hearty Tex-Mex inspired casserole is easy to make and packed with bold, satisfying flavors.


Ingredients

  • 1 (16.3-ounce) can refrigerated biscuits
  • 2 pounds ground beef
  • 1 (1-ounce) packet taco seasoning
  • ¾ cup water
  • 1 medium onion, halved and sliced
  • 1 medium red bell pepper, halved and sliced
  • ½ cup sour cream
  • ½ cup mayonnaise
  • 8 ounces shredded Cheddar cheese, divided
  • 2 medium tomatoes, sliced
  • 1 (4-ounce) jar sliced jalapeño peppers, drained (optional)

Instructions

  1. Preheat oven to 350°F (175°C) and lightly grease a 9x13-inch baking dish.
  2. Press biscuit dough into the bottom and slightly up the sides of the dish. Bake for 15–20 minutes or until golden.
  3. In a skillet, brown ground beef over medium-high heat. Drain fat, stir in taco seasoning and water, and simmer for 5 minutes.
  4. In the same skillet, sauté onions and bell pepper until slightly tender.
  5. In a bowl, mix sour cream, mayonnaise, and half the Cheddar cheese.
  6. Layer in the baking dish: taco meat, tomato slices, sautéed veggies, jalapeños (if using), then the sour cream mixture. Top with remaining cheese.
  7. Bake uncovered for 30–40 minutes, until cheese is melted and edges are golden brown.

Notes

  • Swap ground beef for ground turkey or plant-based alternatives.
  • Add black beans or corn for a heartier texture.
  • Top with crushed tortilla chips for crunch.
  • Can be prepped ahead and stored in the fridge overnight.
  • To reduce spice, omit jalapeños and use mild seasoning.