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Slow Cooker Beef Brisket with Homemade BBQ Sauce

Published: May 4, 2025 by Sue · This post may contain affiliate links · Leave a Comment

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This Slow Cooker Beef Brisket recipe delivers tender, juicy, and flavor-packed meat, enhanced by a smoky spice rub and a homemade barbecue sauce. It's an effortless yet impressive dish perfect for any occasion.

Slow Cooker Beef Brisket with Homemade BBQ Sauce

Why I Love This Recipe

I appreciate how this recipe transforms a tough cut of meat into a succulent, melt-in-your-mouth delight with minimal effort. The combination of a robust spice rub and a tangy homemade BBQ sauce creates a depth of flavor that's hard to resist. Plus, the make-ahead option makes entertaining stress-free.

Ingredients

(Here's a tip: Check out the full list of ingredients and measurements in the recipe card below.)

For the Brisket:

  • 4-5 pounds beef brisket, trimmed of excess fat
  • 1 cup water
  • 1 tablespoon beef bouillon
  • 2 tablespoons Worcestershire sauce
  • 1 tablespoon reduced sodium soy sauce
  • ½ cup homemade barbecue sauce (see below)

For the Spice Rub:

  • 2 tablespoons paprika
  • 2 tablespoons packed brown sugar
  • 1 tablespoon chili powder
  • 2 teaspoons garlic powder
  • 2 teaspoons salt
  • 1 teaspoon onion powder
  • 1 teaspoon chipotle powder
  • 1 teaspoon black pepper
  • ½ teaspoon dried thyme
  • ¼ teaspoon cayenne pepper (optional)

For the Homemade Barbecue Sauce:

  • 1 ½ cups ketchup
  • ⅓ cup molasses
  • ⅓ cup packed brown sugar
  • ¼ cup seedless blackberry preserves
  • ¼ cup apple cider vinegar
  • 1 tablespoon reserved spice rub
  • 1 tablespoon mesquite liquid smoke (optional)

Directions

  1. Prepare the Spice Rub: In a medium bowl, combine all the spice rub ingredients. Reserve 1 tablespoon for the barbecue sauce.
  2. Season the Brisket: Rub the remaining spice mix evenly over the brisket. Place the seasoned brisket on a baking sheet lined with parchment paper or foil.
  3. Sear the Brisket: Preheat the oven to 425°F (220°C). Bake the brisket uncovered for 30 minutes to develop a flavorful crust.
  4. Make the Barbecue Sauce: In a medium bowl, whisk together all the barbecue sauce ingredients, including the reserved tablespoon of spice rub.
  5. Prepare the Slow Cooker: Spray a 6-quart (or larger) slow cooker with non-stick cooking spray. Add ½ cup of the barbecue sauce, water, Worcestershire sauce, soy sauce, and beef bouillon. Stir to combine.
  6. Slow Cook the Brisket: Transfer the seared brisket to the slow cooker, nestling it into the sauce. Cover and cook on low for 8-10 hours, flipping halfway through, until the brisket is very tender.
  7. Caramelize the Brisket: Remove the brisket from the slow cooker and place it on a foil-lined baking sheet. Brush with additional barbecue sauce and broil for 5-10 minutes until slightly caramelized.
  8. Serve: Slice the brisket against the grain or shred it, and serve with the remaining warmed barbecue sauce.

Servings and Timing

  • Servings: 8-10
  • Prep Time: 15 minutes
  • Cook Time: 8-10 hours
  • Total Time: Approximately 8 hours 15 minutes

Variations

  • Spicy Kick: Add extra cayenne pepper or hot sauce to the spice rub for more heat.
  • Sweet Touch: Incorporate honey or maple syrup into the barbecue sauce for added sweetness.
  • Different Cuts: Substitute beef brisket with chuck roast if desired.

Storage/Reheating

  • Storage: Store leftover brisket in an airtight container in the refrigerator for up to 4 days.
  • Freezing: Freeze in a freezer-safe container for up to 3 months. Thaw in the refrigerator before reheating.
  • Reheating: Warm the brisket in a slow cooker on low for 1-2 hours or in the oven at 325°F (160°C) until heated through.

FAQs

What if I don't have a slow cooker?

I can cook the brisket in a Dutch oven or oven-safe pot. After searing, add the sauce ingredients, cover, and bake at 300°F (150°C) for 3-4 hours until tender.

Can I make this recipe ahead of time?

Yes, I often cook the brisket a day in advance, refrigerate it in its juices, and then reheat it in the slow cooker on low for 1-2 hours before serving.

What sides pair well with this brisket?

I enjoy serving it with coleslaw, mashed potatoes, roasted vegetables, or on a bun as a sandwich.

Can I use store-bought barbecue sauce?

While homemade sauce enhances the flavor, I can use my favorite store-bought barbecue sauce in a pinch.

How do I know when the brisket is done?

The brisket is done when it's very tender and easily shreds with a fork. If it's still tough, I let it cook longer.

Conclusion

This Slow Cooker Beef Brisket recipe is a game-changer for effortless, flavorful meals. The combination of a smoky spice rub and homemade barbecue sauce creates a dish that's both comforting and impressive. Whether for a family dinner or entertaining guests, this brisket is sure to be a hit.

Print

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Slow Cooker Beef Brisket with Homemade BBQ Sauce

Slow Cooker Beef Brisket with Homemade BBQ Sauce

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  • Author: Sue
  • Prep Time: 15 minutes
  • Cook Time: 8–10 hours
  • Total Time: ~8 hours 15 minutes
  • Yield: 8–10 servings
  • Category: American, Southern
  • Method: Slow Cooker
  • Cuisine: American, Southern
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Description

Slow Cooker Beef Brisket with Homemade BBQ Sauce is the ultimate comfort food, featuring a smoky spice rub, tender slow-cooked meat, and a tangy, sweet barbecue sauce. Perfect for entertaining or family dinners, this melt-in-your-mouth brisket is a flavor-packed crowd-pleaser.


Ingredients

  1. For the Brisket:
  2. 4–5 pounds beef brisket, trimmed of excess fat
  3. 1 cup water
  4. 1 tablespoon beef bouillon
  5. 2 tablespoons Worcestershire sauce
  6. 1 tablespoon reduced sodium soy sauce
  7. ½ cup homemade barbecue sauce
  8. For the Spice Rub:
  9. 2 tablespoons paprika
  10. 2 tablespoons packed brown sugar
  11. 1 tablespoon chili powder
  12. 2 teaspoons garlic powder
  13. 2 teaspoons salt
  14. 1 teaspoon onion powder
  15. 1 teaspoon chipotle powder
  16. 1 teaspoon black pepper
  17. ½ teaspoon dried thyme
  18. ¼ teaspoon cayenne pepper (optional)
  19. For the Homemade Barbecue Sauce:
  20. 1 ½ cups ketchup
  21. ⅓ cup molasses
  22. ⅓ cup packed brown sugar
  23. ¼ cup seedless blackberry preserves
  24. ¼ cup apple cider vinegar
  25. 1 tablespoon reserved spice rub
  26. 1 tablespoon mesquite liquid smoke (optional)

Instructions

  1. Mix Spice Rub: Combine all spice rub ingredients; set aside 1 tablespoon for BBQ sauce.
  2. Season Brisket: Coat brisket evenly with spice rub. Place on lined baking sheet.
  3. Sear: Bake at 425°F (220°C) for 30 minutes uncovered.
  4. Make BBQ Sauce: Whisk all sauce ingredients in a bowl.
  5. Prep Slow Cooker: Add ½ cup BBQ sauce, water, Worcestershire, soy sauce, and bouillon. Stir.
  6. Slow Cook: Add brisket to the slow cooker. Cover and cook on low for 8–10 hours, flipping halfway.
  7. Broil: Remove brisket, brush with BBQ sauce, and broil for 5–10 minutes until caramelized.
  8. Serve: Slice or shred brisket and serve with remaining warm BBQ sauce.

Notes

  • Store leftovers in an airtight container in the fridge for up to 4 days.
  • Freeze brisket in a freezer-safe container for up to 3 months.
  • Reheat in the oven or slow cooker until heated through.
  • Make ahead and reheat for easy entertaining.

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Hey there! I'm Sue, a mom, a wife, and someone who’s always in the kitchen trying out new recipes or revisiting old ones that remind me of family gatherings and special moments.

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